About

Valo Therapeutics (ValoTx)

is a spin-out company from the IVTLab at the University of Helsinki, Finland. ValoTx has assembled a uniquely talented team of oncolytic virus and immunotherapy experts, who together with the founding scientist have the necessary expertise to take its patented technology through clinical development and make it available to patients. The management team has a proven track record of developing successful companies from a laboratory idea to a full stock exchange listing.

The Business Concept

ValoTx is positioned to transform the field of immunotherapy in cancer. ValoTx’s technology uniquely combines the best qualities of several distinct clinically proven immunotherapy concepts – oncolytic virus therapy, peptide vaccination and viral vector-based immunotherapy. Our technology platform is able to deliver many different antigens through coating the surface of a wide range of vectors, including but not limited to adenoviruses, enveloped viruses and bacteria

Technology

ValoTx’s proprietary technology allows the binding of disease-targeting peptides to the surface of oncolytic vectors, thereby eliciting an enhanced T-cell driven immune response to destroy the targeted tumor. The disease associated peptides are easily and rapidly combined with the vector by leveraging electrostatic interactions and membrane penetrating peptides rather than through generating disease antigens by genetically engineering the vector. This method enables the rapid creation of multiple vector-based immunotherapies that promise to provide lasting immunity to many different cancer types. This approach also addresses the need for rapidly adaptable disease-specific and even personalised therapies.

Our team

Paul G Higham
Paul G Higham
Chief Executive Officer
Biography

Paul G Higham

Chief Executive Officer

Paul G Higham

Paul G Higham, Chief Executive Officer, is a seasoned healthcare industry expert with extensive leadership experience in both large pharmaceutical and biotech companies. He has over 15 years C-Suite Biotech company experience. During the last 10 years he has been CEO of two immuno-oncology development-stage companies. In more detail:

He was Chief Executive Officer of Glycotope GmbH a glycobiology company focussing on immuno-therapeutics in oncology from 2016 to 2017 and before that CEO at Immatics Biotechnologies from 2008 to 2015. Through his leadership at Immatics, the company developed a number of peptide-based immunotherapies and has become one of the leading T-cell focused cancer immunotherapy companies. Previously, he served as Director Commercial Development at Ark Therapeutics Group plc where he was responsible for commercial strategy and all business development activities. In addition, he was in charge of establishing the operations and adenovirus gene-based medicine production facilities of Ark Therapeutics in Finland (Kuopio). Before joining Ark Therapeutics in 2001, Paul G Higham worked as International Commercial Vice President for GI, Metabolic and Pain at GlaxoWellcome plc/GSK, where he was responsible for all aspects of international commercial strategy. Prior to that he held various sales and marketing positions with increasing responsibilities with Bayer AG becoming General Manager of Bayer Pharmaceuticals for Sweden and Denmark. He holds an honours degree in Applied Biology.

Paul G Higham
Sari Pesonen
Sari Pesonen (PhD)
Chief Scientific Officer
Biography

Sari Pesonen (PhD)

Chief Scientific Officer

Sari Pesonen

Sari Pesonen, Chief Scientific Officer (PhD, co-founder), has held scientific leadership roles in immuno-oncology biotech companies and has vast experience in clinical drug development. She joined Oncos Therapeutics as a Research Director and later took on the role of Head of Clinical Science, leading clinical sample analysis, which for the first time demonstrated the mode of action of oncolytic adenovirus-based cancer immunotherapy. Later, Sari worked as VP Preclinical Research and Clinical Science at Targovax. Sari gained her PhD in biology from the University of Turku, Finland in 2007. She continued her academic career at the University of Helsinki in a research group focusing on the development of oncolytic viruses for the treatment of cancer. She has supervised 3 PhD students and is a co-author on 60 peer-reviewed research papers.

Sari Pesonen
Hemanshu Shah
Hemanshu Shah (PhD)
Chief Business Officer
Biography

Hemanshu Shah (PhD)

Chief Business Officer

Hemanshu Shah

Hemanshu Shah, Chief Business Officer, is an executive with more than 30 years’ experience, in both large pharmaceutical companies (Bristol-Myers Squibb, Johnson & Johnson and Astellas) and emerging biotechnology companies (GPC Biotech, Innate Pharma and Transgene). He is currently a member of the Supervisory Board of Modra Pharmaceuticals B.V. Hemanshu has experience across multiple functional areas including drug development, strategic marketing, business development and commercial operations (US and global marketing).  In addition to substantial experience in the oncology therapeutic area, he also has experience in immunology, transplantation and infectious diseases. Hemanshu brings a track record of successful corporate development and business development transactions. Hemanshu has a PhD in Pharmaceutical Sciences from Rutgers University (NJ, USA) and an MBA from the University at Buffalo (NY, USA).

Hemanshu Shah
Charlotta Backman
Charlotta Backman (M.Sc)
VP Clinical Operations and Regulatory Affairs
Biography

Charlotta Backman (M.Sc)

VP Clinical Operations and Regulatory Affairs

Charlotta Backman

Charlotta Backman, VP Clinical Operations and Regulatory Affairs, has a strong background in clinical research with 15 years of experience in the start-up, conduct, and close-out of Phase I to Phase IV clinical trials, mostly including trials in oncology and vaccines. Over the years, she has gained experience from interactions with several regulatory authorities in the EU and in the US. Charlotta worked in the CRO industry for Encorium and Remedium, managing clinical trials in various phases and indications before taking on the responsibility for management of the clinical trials with oncolytic adenoviruses at Oncos Therapeutics (later Targovax). Charlotta has a Master’s degree in Cell Biology from Åbo Akademi University. During her academic career, Charlotta worked as a Researcher and Project Team Leader at the University of Helsinki and Folkhälsan Institute of Genetics in the field of disease genetics.

Charlotta Backman
Petri Priha
Petri Priha (Lic.Sc)
VP of CMC
Biography

Petri Priha (Lic.Sc)

VP of CMC

Petri Priha

Petri Priha, VP of CMC, has over 20 years’ experience in expert and management positions in vaccine, biopharmaceutical protein, and oncolytic adenovirus process development and GMP manufacturing. Prior to joining Valo Therapeutics in January 2017, Petri served as VP of CMC at Targovax, and before that as Director of Process Development and Quality Assurance at Oncos Therapeutics. During his 5 years at Oncos, he was responsible for the CMC development of an oncolytic adenovirus cancer immunotherapy platform. Petri also served at Ipsat Therapies for 9 years as Director of Production and Quality of prophylactic biopharmaceutical proteins targeted to prevent antibiotic-associated secondary infections. Prior to that, he worked at the National Institute for Health and Welfare, where he was responsible for bacterial vaccine manufacturing. Petri is a chemical engineer (Lic. Sc. Tech.) from Helsinki University of Technology.

Petri Priha
Dr Lukasz Kuryk
Lukasz Kuryk (PhD)
VP Translational and Clinical Science
Biography

Lukasz Kuryk (PhD)

VP Translational and Clinical Science

Dr Lukasz Kuryk

Lukasz Kuryk, VP Translational and Clinical Science, holds a PhD in biopharmaceutics/oncolytic virotherapy from University of Helsinki, Finland. He also earned his MBA diploma from the Institute of Computer Science PAN, Poland and Woodbury School of Business, UT, USA. Dr Kuryk brings experience in immuno-oncology and immuno-virotherapy, knowledge of preclinical, translational and early-stage clinical drug development in oncology (Phase I and II). Before joining Valo Therapeutics, he worked for last 10 years in clinical stage immuno-oncology companies Targovax (Director, Clinical Science) and Oncos Therapeutics (Research Scientist), on both pre-clinical research and clinical studies utilizing oncolytic vectors and peptide vaccines for cancer treatment. Mr Kuryk also worked at the Institute of Biomedical Research ‘’Alberto Sols’’, Spain, the Military Institute of Hygiene and Epidemiology, Poland. He was also a visiting researcher at the Regional WHO/Europe at the Robert Koch Institute, Germany, Bellvitge Biomedical Research Institute (IDIBELL), Spain, and University of Padova, Italy where conducing numerous research projects in the field of immuno-oncology and virology. Dr Kuryk is an Assistant Professor at the National Institute of Public Health, Poland, being responsible for several research projects in the field of immunotherapy. Lukasz is a Polish citizen and resides in Finland.

Dr Lukasz Kuryk
Otto Kari
Otto Kari (PhD)
VP, Head of Antigen Business Unit
Biography

Otto Kari (PhD)

VP, Head of Antigen Business Unit

Otto Kari

Otto Kari, VP & Head of Antigen Business Unit, holds a Ph.D. in Pharmacy from the University of Helsinki, Finland. He has over 15 years of experience in pharmaceutical research and development, with advanced qualifications in R&D and technology management. During his Ph.D. and post-doctoral studies, he developed and set up novel and innovative methods and infrastructure for the study of biocorona formation on nanotechnological drug delivery systems and viruses. Recently, he served as the Commercial Lead for PeptiCHIP, a microfluidics-based technology for rapid tumor antigen identification developed by Prof. Vincenzo Cerullo’s ImmunoTherapyLab at University of Helsinki.     Previously, Dr Kari has served as a visiting researcher or teacher at the Institute of Environmental Medicine, Karolinska Institutet, Sweden (systems toxicology), and Department of Industrial Engineering and Management, Aalto University, Finland (strategic technology management). He has authored over 13 peer-reviewed articles covering fields such as cancer immunotherapy, pharmaceutical nanotechnology, drug delivery, biophysics, and medical logistics. Dr Kari is also a Laboratory Director for PharmaHUB at the Faculty of Pharmacy, University of Helsinki, and Chairman of the Council at the Finnish Red Cross. 

Otto Kari
Matthew Vaughan
Matthew Vaughan (PhD)
Business Operations Director
Biography

Matthew Vaughan (PhD)

Business Operations Director

Matthew Vaughan

Matthew Vaughan, Business Operations Director, gained his PhD in Geology at the University of Otago, New Zealand, in October 2016 while working part-time for the company. His academic research involved the study of microstructural mechanics and velocity anisotropy in deforming ice, and its relationships to the large scale flow of ice sheets. Matthew has completed research exchanges at University College London, Oxford University, and MIT, and has participated in deep field expeditions to the Arctic and Antarctica. During his PhD, he co-supervised several students, lead the construction of two new labs, and helped develop several apparatus for performing low temperature deformation experiments on ice. To date, Matthew is the co-author of seven peer-reviewed research papers and has received funding support from the Royal Society of New Zealand, NASA, and the European Science Foundation. Matthew joined Valo Therapeutics shortly after the company was founded, to assist the team across all aspects of the business.

Matthew Vaughan
Leena Ylosmaki
Leena Ylösmäki (PHD)
Director Pre-clinical Development
Biography

Leena Ylösmäki (PHD)

Director Pre-clinical Development

Leena Ylosmaki

Leena Ylösmäki, Director of Pre-clinical Development, has over 15 years of experience in the fields of basic and applied virology and cancer research. During her academic career, she has studied various different viruses including Influenza A, vaccinia and adenoviruses. Before joining Valo Therapeutics, Leena worked as a PhD researcher at the university of Helsinki where she designed and developed various oncolytic viruses for cancer immunotherapy. Leena earned her PhD in virology from the Faculty of Medicine at the University of Helsinki.

Leena Ylosmaki
joseph
Joseph Ndika (PhD)
Senior Scientist, Antigen Analytics
Biography

Joseph Ndika (PhD)

Senior Scientist, Antigen Analytics

joseph

Joseph Ndika, Senior Scientist, Antigen Analytics holds a PhD in Clinical Chemistry from Vrije University Medical Center, Amsterdam, Netherlands. Dr Ndika has over 14 years of experience using proteomics (mass spectrometry) and transcriptomics (next generation sequencing, microarrays) profiling of clinical samples to; study perturbation of biological pathways in rare genetic disorders, unravel allergic disease mechanisms and identify diagnostic biomarkers of adverse environmental exposures. Prior to joining Valo Therapeutics, Dr Ndika has worked on projects to develop in vitro assays to study genetic adaptation (FOM-AMOLF, Netherlands), and predict the pathogenicity of novel gene mutations associated with inborn genetic errors of metabolism (VUMC, Netherlands). In the last 6 years, his research activities have been primarily situated at the University of Helsinki, where he optimized/developed liquid chromatography mass spectrometry methods to study nanoparticle-protein interactions, investigate respiratory allergy biomarkers in patient-derived nasal brush/biopsy samples, or identify allergens from biological pesticides. He is co-author on over 27 peer-reviewed publications.

joseph
Petra Ahokas
PETRA AHOKAS (M.SC)
Laboratory Manager
Biography

PETRA AHOKAS (M.SC)

Laboratory Manager

Petra Ahokas

Petra Ahokas, Laboratory Manager, has over 10 years of experience working in laboratories, both as a research assistant and as a scientist, mostly in the field of cancer research. She joined Valo Therapeutics in 2018 and was tasked with opening and managing Valo's new research and development laboratory. Before joining Valo Therapeutics, Petra worked in cancer research at the University of Helsinki and extensively with oncolytic viruses as a Research Scientist at Oncos Therapeutics (now Targovax). Prior to that, she worked at the National Public Health Institute of Finland in the Department of Vaccines. Petra has a Master’s degree in Biology from the University of Helsinki.

Petra Ahokas
Hanne Cojoc
Hanne Cojoc (M.Sc. Tech)
QA Manager / Technical Scientist
Biography

Hanne Cojoc (M.Sc. Tech)

QA Manager / Technical Scientist

Hanne Cojoc

Hanne Cojoc, QA Manager/Technical Scientist, holds an M.Sc. (Tech) in Bioengineering from Tampere University, Finland. She has gained broad QA experience ranging from pharmaceutical development to healthcare technology. Hanne has also extensive experience in bio-technical laboratory work in both the clinical and pre-clinical settings. She has formerly worked at HUSLAB Laboratories in Finland and has vast experience in research environments such as Tampere University and the University of Helsinki's Centre of Excellence in Stem Cell Metabolism (where she conducted her Master’s thesis research).

 

Hanne Cojoc
Suvi
Suvi Karumo (M.Sc)
Laboratory Scientist, Antigen Business Unit
Biography

Suvi Karumo (M.Sc)

Laboratory Scientist, Antigen Business Unit

Suvi

Suvi Karumo, Laboratory Scientist, holds an M.Sc in Pharmacy from the University of Helsinki with a major in Biopharmacy. Before joining Valo Therapeutics as a Laboratory Scientist in Antigen Business Unit, she has worked as a Research Assistant and Project Researcher in Drug Delivery Group of the University of Helsinki. Her academic work and master’s thesis research involved investigating nanoparticle-mediated drug delivery systems for cancers and eye diseases, with the main focus on liposomal nanocarriers for controlled delivery of peptide-based immunotherapeutic and angiogenesis-inhibiting anticancer drugs.

Suvi
Philip Stanecki
Philip Stanecki (M.Sc)
Accounting Manager
Biography

Philip Stanecki (M.Sc)

Accounting Manager

Philip Stanecki

Philip Stanecki, Accounting Manager, holds an M.Sc in Economics and Business Administration (International Business) from Copenhagen Business School. Before joining the Valo Therapeutics team as an Accounting Manager, he worked as an accountant at a licensed accounting office, as well as an auditor at a Big 4 firm in Helsinki. He has been working with listed and large non-listed audit clients over the past few years from a broad range of industries. Philip brings his skills and knowledge in accounting as well as working in an international team from his many years of travel and living abroad.

Philip Stanecki
Kalle
Kalle Manninen (M.Sc)
Technical Scientist
Biography

Kalle Manninen (M.Sc)

Technical Scientist

Kalle

Kalle Manninen, Technical Scientist, holds an M.Sc. in Pharmacy from the University of Helsinki with a major in Biopharmacy. During his studies he was chosen to the researcher line in the Faculty of Pharmacy, so he has worked as a Research Assistant in several research projects, where most of his professional time was used on utilizing Surface plasmon resonance and Raman spectroscopy in characterization of extracellular vesicles and polymer brushes. Kalle was first introduced to Valo Therapeutics as a seasonal worker to establish an isothermal titration calorimetry method for biophysical characterization of PeptiCRAd complexes, which ultimately ended up being the topic of his master's thesis. Following his graduation he continues developing methods of analysis for elucidating PeptiCRAd properties and complexation. 

Kalle
Sandeep
Sandeep Kumar (PhD)
Research Scientist II
Biography

Sandeep Kumar (PhD)

Research Scientist II

Sandeep

Sandeep Kumar, Research Scientist II, holds a PhD degree in Biochemistry and his academic
research work was focused on drug discovery. He authored several research articles,
reviews and book chapters in peer reviewed journals. After graduation in 2019, he served as
an Assistant Professor of Biochemistry in veterinary research institute in India. In 2020, he
joined as a Research Scientist in Clinical Science department of Targovax, a clinical stage
immuno-oncology company. He was responsible for planning and execution of preclinical
projects on newly constructed adenoviruses. He was also involved in clinical data analysis of
Targovax’s lead clinical candidate, ONCOS-102, a genetically modified oncolytic adenovirus.
He brings his expertise in preclinical and early-stage clinical drug development to Valo.

Sandeep

Board of Directors

Matti Hautsalo
Matti Hautsalo
Chairman of the Board
Biography

Matti Hautsalo

Chairman of the Board

Matti Hautsalo

Matti Hautsalo is a Director at Bentmind Development, which is an investor and a development partner with early stage high technology companies, assisting them to build an international management team and to partner with high value-adding actors in science, industry and investment. Bentmind Group is involved with companies in fields covering AI, big data analysis, oncolytics, cell description optimisation, and medical imaging.

Matti has been involved with high technology start-up investments since the start of the millennium, including working as a partner at the privately owned Finnish VC company, Aura Capital from 2006-2013. There he held chairmanships and directorships in several companies with science based IP assets and technologies, from live-cell imaging to material sciences and software businesses. Matti is also an advisor of Confido Capital, a boutique asset management house regulated by the Finnish FSA. Prior to his startup life, Matti worked at McKinsey&Co and ING Asset Management. He holds an M.Sc. in Economics from the University of Helsinki and UA de Madrid.

Matti Hautsalo
Anthony Giovinazzo
Anthony Giovinazzo
Member of the Board
Biography

Anthony Giovinazzo

Member of the Board

Anthony Giovinazzo

Mr. Anthony J. Giovinazzo, MBA, C. Dir. & A.C.C., has 43 years of total work experience, is an internationally recognized expert in intellectual property, drug development and commercialization, including numerous licensing agreements and M&A, with more than 25 years’ experience in Central Nervous System diseases. He was most recently, the co-inventor, Chief Executive Officer and Director of Cynapsus Therapeutics, a NASDAQ listed specialty pharmaceutical company that developed the first successful sublingual apomorphine thin film strip for Parkinson’s disease. The drug is approved for commercialization by the United States Food and Drug Administration and Health Canada. Mr. Giovinazzo was a co-inventor of the drug, built the leadership team, set the strategy, raised US $ 136 million including an oversubscribed IPO and NASDAQ listing. He led the negotiations with several pharmaceutical companies that resulted in the Cdn. $ 841 million all cash acquisition by Sunovion Pharmaceuticals (Dainippon Sumitomo Pharmaceuticals). A 120% premium to market close on the day of announcement.

He is currently the Executive Chairman of Kalgene Inc., a Canadian/American private specialty pharmaceutical company focused on Alzheimer’s disease. Kalgene’s lead program KG207 is currently being evaluated as a potential best-in-class drug candidate for early to moderate Alzheimer’s.

He is Chairman of the Board of Xortx Therapeutics Inc. (TSXV: XRTX) (NASDAQ: XRTX) a late-stage clinical pharmaceutical company focused on developing innovative therapies to treat progressive kidney disease.

He is a Director on the Board of Titan Medical Inc. (TSX: TMD.TO) (NASDAQ: TMDI) a developer of a cutting-edge leading robotics assisted single port surgery system (the Enos System).

Mr. Giovinazzo has raised more than US $ 825 million in private and public equity. He was a Canadian finalist in Life Sciences for the E&Y Entrepreneur of the Year (2014). In 2017 he was the recipient of the Finance Monthly Game Changers award as well as having been chosen as the inaugural recipient of the Bloom Burton Award, which honors the best of the best in Canadian Life Sciences as judged by a panel of US experts. He is a Chartered Director and Audit Committee Certified, both from The Directors College, a degree granting affiliate of Mc Master University, Hamilton Canada. He also has completed the Leadership and Strategy in Pharmaceuticals and Biotech, in 2006 from Harvard Business School, Boston, MA; a Master of Business Administration from IMD, Geneva Switzerland in 1986; a Graduate Certificate Studies in Canadian Law from Osgoode Hall Law School, York University, Toronto, ON. 1984; and a Bachelor of Arts in Economics and Accounting at McMaster University, 1978. 

Anthony Giovinazzo
Paul Porter
Dr. Paul Porter
Member of the Board
Biography

Dr. Paul Porter

Member of the Board

Paul Porter

Associate Professor Paul Porter (MBBS, FRACP), Director, is the founder of Freeman Road Pty Ltd, an Australian company that specialises in early stage biomedical investments with an emphasis on global research and development collaborations. Freeman Road has investments in companies across Australia, South East Asia, Europe and the USA.

Paul is an experienced medical researcher, lecturer, director of training and paediatric physician at two major paediatric hospitals in Western Australia. He leads an established a research unit specialising in novel biometric diagnostic technology and algorithm development, with active programs targeting respiratory disease, antenatal care and mental health disorders in children and adolescents. He is the Chair of the Ramsay Health Care Human Research and Ethics Committee for Western and South Australia.

He is passionate about supporting advances in healthcare in the developing world.

Paul Porter
David Hinton
David Hinton
Member of the Board
Biography

David Hinton

Member of the Board

David Hinton

David is an experienced executive in the ASX listed environment. He is currently CFO and Company Secretary of Empired Ltd (ASX: EPD) an international IT services provider a position he has held since 2016.  Prior to that he was CFO and Company Secretary of Amcom Telecommunications Ltd (ASX: AMM) since 2008 until taken over by Vocus Communications in 2015. In these positions David has played a key role in the implementation of systems and processes to ensure that financial information is accurate and timely so that commercial decisions can be made in a robust manner. This has enhanced the ability of these two companies to grow in a scalable and sustainable manner. During his time at Amcom it grew from a small ISP in the period, post the de-regulation of the telco industry, to being a true challenger brand by 2015. With the explosion in the demand for data, internet connectivity and Cloud, Amcom built an extensive last mile nationwide fibre network with 10 data centres and developed many adjacent services.  David had a key role in ensuring that the organic and inorganic growth was appropriately funded and that acquisitions were suitably integrated. David also oversaw the legal, compliance and regulatory functions at Amcom a role he also undertakes at Empired. 

David also has extensive corporate experience and has been heavily involved in numerous M&A transactions, IPO’s, and capital and debt raisings. In his role as Company Secretary, he is very familiar with the workings of Boards and governance matters. Prior to 2008, David held senior positions at the diversified industrial Futuris Corporation Ltd and prior to that worked in London and was a Manager at Ernst & Young. He holds a Bachelor of Business degree, is a Fellow of the Institute of Chartered Accountants in Australia and New Zealand, Graduate of the Australian Institute of Company Directors, and a Graduate of the Governance Institute of Australia.

David Hinton

Scientific Advisors

Vincenzo Cerullo
Prof. Vincenzo Cerullo
Chairman of the Valo Tx Scientific and Clinical Advisory Board
Biography

Prof. Vincenzo Cerullo

Chairman of the Valo Tx Scientific and Clinical Advisory Board

Vincenzo Cerullo

Prof. Vincenzo Cerullo (Vince), Scientific Founder, is a Professor in Biological Drug Development, Head of the Drug Research Program and a HiLIFE Fellow, Translational Immunology Programme at the University of Helsinki.

Vince gained his PhD at the Centre for Genetic Engineering (CENIGE) at the University of Naples, Federico II in 2004. He then moved to Houston Texas (USA), where he completed a Postdoc at the Baylor College of Medicine. Later, he moved to the University of Helsinki and in 2012 was awarded a tenure-track professorship, opening the ImmunoViroTherapy Lab. IVTLab has raised more than 5 million Euros for research, including the prestigious ERC Consolidator Grant, the HiLIFE Fellowship and the Jane and Aatos Erkko Foundation grant. Vince received the Outstanding Young Investigator award in 2014 from the European Society of Gene and Cell Therapy, as well as the Excellence in Research Award from the American Society of Gene and Cell Therapy in 2015.

One of Vince’s passion is science dissemination. He has been involved from the beginning in the organisation of the Science Track at the Slush conference in Helsinki. Vince pitched on the Slush stage in 2015 and 2016 and on the Slush Y Science stage in 2017 (www.slush.org). Among others, he has presented a TEDx talk on the importance of creativity in science (https://youtu.be/1btbElPnREI ).

Vincenzo Cerullo
P Ascierto
Prof. Paolo Antonio Ascierto
Member of the Scientific and Clinical Advisory Board
Biography

Prof. Paolo Antonio Ascierto

Member of the Scientific and Clinical Advisory Board

P Ascierto

Prof. Paolo Antonio Ascierto is a world-leading key opinion leader in melanoma disease and immunotherapy. He is currently Director of the Department of Melanoma, Cancer Immunotherapy and Development Therapeutics at the National Cancer Institute “Pascale” in Naples, Italy. He is Editorial Board Member, Editor and Scientific Reviewer for leading medical journals and a member of the Steering Committee of the Society of Melanoma Research (SMR). Dr Ascierto is part of the Board of Directors for the Society of ImmunoTherapy of Cancer (SITC) and of the Cancer Development Drug Forum (CDDF), and is President of the Fondazione Melanoma Onlus, and the Campania Society of ImmunoTherapy of Cancer (SCITO). He has been an invited speaker to over 400 national and international scientific meetings, courses, and workshops. He has presided as Principle Investigator on over 150 clinical trials, and he is the author of over 600 publications in peer-reviewed journals. His awards and honours are numerous and include receiving the GEF Health Award in 2022. He has received funding from the POR FESR and ERA-NET, among others.

P Ascierto
J Bockman
Dr Jeffrey Bockman
Member of the Scientific and Clinical Advisory Board
Biography

Dr Jeffrey Bockman

Member of the Scientific and Clinical Advisory Board

J Bockman

Dr Jeffrey Bockman received a BA from the University of California at San Diego, an MA in English/Creative Writing from New York University, and a PhD in Medical Microbiology from the University of California at Berkeley. He is the Executive Vice President, Head of Oncology at Lumanity BioConsulting, and was an Assistant Research Professor at The George Washington University School of Medicine. He has worked closely with two Nobel Prize recipients: Dr Sidney Altman, on ribozymes, and Dr Stanley Prusiner, on prions. He brings to the SAB extensive commercial and strategic perspective on the pharmaceutical and biotech industries, including leading the commercial development of oligonucleotide therapeutics for viral diseases and cancer at Innovir Laboratories. He is a frequent speaker at industry events such as BIO on the intersection of scientific, clinical, and strategic issues affecting biotech oncology drug development. Jeff is a member of AACR, ASCO, ASH, ASGCT, SITC and NYAS. He is a mentor for the NCI Innovation Conference, a judge for the Citeline Awards, a member of the Advisory Group to Skipper Bio Med, and is on the Clinical Advisory Board of ImmunOS (Zurich) and the Scientific Advisory Board of hC Bioscience (Cambridge, MA).

J Bockman
Malcolm Brenner
Prof. Malcolm K. Brenner
Member of the Scientific and Clinical Advisory Board
Biography

Prof. Malcolm K. Brenner

Member of the Scientific and Clinical Advisory Board

Malcolm Brenner

Prof. Malcom K. Brenner is an award-winning physician-scientist who has pioneered the therapeutic use in cancer of T cell immunologic approaches and genetic engineering strategies.  He is the Founding Director, Centre for Cell and Gene Therapy, Baylor College of Medicine (BCM), Houston Methodist Hospital and Texas Children’s Hospital. He served as Editor-in-Chief of Molecular Therapy and as former President of the American Society for Gene and Cell Therapy and of the International Society for Cell Therapy. Dr Brenner obtained his medical degrees and PhD from the University of Cambridge, England. Dr Brenner’s work has been funded by the NIH-NCI, the Leukemia and Lymphoma Society, the Cancer Prevention and Research Institute of Texas, and several charitable foundations. He has been involved in the foundation of several companies, such as Allovir, Marker Therapeutics, and Tessa Therapeutics.

Malcolm Brenner
K Harrington
Prof. Kevin Harrington
Member of the Scientific and Clinical Advisory Board
Biography

Prof. Kevin Harrington

Member of the Scientific and Clinical Advisory Board

K Harrington

Prof. Kevin Harrington qualified in medicine from the University of London and obtained his PhD from Imperial College, London. He is a Fellow of the Royal College of Physicians and the Royal College of Radiologists. He completed postgraduate training in clinical oncology (Royal College of Radiologists Rohan Williams medallist) and postdoctoral research in Professor Richard Vile’s laboratory at the Molecular Medicine Programme in the Mayo Clinic. He subsequently was appointed to a group leader position at The Institute of Cancer Research (ICR), London and an honorary consultant oncologist post at the Royal Marsden Hospital (RMH). He is the Head of the Division of Radiotherapy and Imaging at the ICR, and Director of the CRUK ICR/RMH RadNet Centre of Excellence. He has led phase I, II and III trials of oncolytic virotherapies, immunotherapy and radiation-drug combinations. He brings to the SAB a longstanding focus on gene therapy and viral gene therapy as ways to selectively destroy cancer cells and activate anti-tumour immune responses. His laboratory research focuses on the use of biologically targeted agents, in combination with treatments such as radiotherapy and chemotherapy, to target cancer cells selectively, especially in head and neck cancer and in melanoma.

K Harrington